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1

A Genetic Screen Implicates miRNA-372 and miRNA-373 As Oncogenes in Testicular Germ Cell Tumors

P. Mathijs Voorhoeve, Carlos le Sage, Mariette Schrier, Ad J.M. Gillis, Hans Stoop, Remco Nagel, Ying-Poi Liu, Josyanne van Duijse, Jarno Drost, Alexander Griekspoor, Eitan Zlotorynski, Norikazu Yabut

Journal:

Year:

2006

Language:

english

File:

PDF, 863 KB

english, 2006

2

CRISPR-Cas9D10A nickase-based genotypic and phenotypic screening to enhance genome editing

Chiang, Ting-Wei Will, le Sage, Carlos, Larrieu, Delphine, Demir, Mukerrem, Jackson, Stephen P.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 3.55 MB

english, 2016

3

Dual direction CRISPR transcriptional regulation screening uncovers gene networks driving drug resistance

le Sage, Carlos, Lawo, Steffen, Panicker, Prince, Scales, Tim M. E., Rahman, Syed Asad, Little, Annette S., McCarthy, Nicola J., Moore, Jonathan D., Cross, Benedict C. S.

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 2.49 MB

english, 2017

4

The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis

Huang, Qihong, Gumireddy, Kiranmai, Schrier, Mariette, le Sage, Carlos, Nagel, Remco, Nair, Suresh, Egan, David A., Li, Anping, Huang, Guanghua, Klein-Szanto, Andres J.

Journal:

Nature Cell Biology

Year:

2008

Language:

english

File:

PDF, 1.78 MB

english, 2008

5

Regulation of the p27Kip1 tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation

le Sage, Carlos, Nagel, Remco, Egan, David A, Schrier, Mariette, Mesman, Elly, Mangiola, Annunziato, Anile, Corrado, Maira, Giulio, Mercatelli, Neri, Ciafrè, Silvia Anna

Journal:

The EMBO Journal

Year:

2007

Language:

english

File:

PDF, 509 KB

english, 2007

6

Methylation-mediated silencing and tumor suppressive function of miR-124 in cervical cancer

Saskia M. Wilting, Robert A.A. van Boerdonk, Florianne E. Henken, Chris J.L.M. Meijer, Begoa Diosdado, Gerrit A. Meijer, Carlos le Sage, Reuven Agami, Peter J.F. Snijders, Renske D.M. Steenbergen

Journal:

Cancer Genetics and Cytogenetics

Year:

2010

Language:

english

File:

PDF, 37 KB

english, 2010

7

miR-376b controls starvation and mTOR inhibition-related autophagy by targeting ATG4C and BECN1

Korkmaz, Gozde, le Sage, Carlos, Tekirdag, Kumsal Ayse, Agami, Reuven, Gozuacik, Devrim

Journal:

Year:

2012

Language:

english

File:

PDF, 3.18 MB

english, 2012

8

RNA-Binding Protein Dnd1 Inhibits MicroRNA Access to Target mRNA

Martijn Kedde, Markus J. Strasser, Bijan Boldajipour, Joachim A.F. Oude Vrielink, Krasimir Slanchev, Carlos le Sage, Remco Nagel, P. Mathijs Voorhoeve, Josyanne van Duijse, Ulf Andersson Ørom, Anders

Journal:

Year:

2007

Language:

english

File:

PDF, 1.88 MB

english, 2007

9

Methylation-mediated silencing and tumour suppressive function ofhsa-miR-124in cervical cancer

Saskia M Wilting, Robert AA van Boerdonk, Florianne E Henken, Chris JLM Meijer, Begoňa Diosdado, Gerrit A Meijer, Carlos le Sage, Reuven Agami, Peter JF Snijders, Renske DM Steenbergen

Journal:

Molecular Cancer

Year:

2010

Language:

english

File:

PDF, 1.50 MB

english, 2010

10

Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity

Léveillé, Nicolas, Elkon, Ran, Davalos, Veronica, Manoharan, Vijayalaxmi, Hollingworth, Dave, Vrielink, Joachim Oude, le Sage, Carlos, Melo, Carlos A., Horlings, Hugo M., Wesseling, Jelle, Ule, Jernej

Journal:

Nature Communications

Year:

2011

Language:

english

File:

PDF, 2.50 MB

english, 2011

11

Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity

Nishi, Ryotaro, Wijnhoven, Paul, le Sage, Carlos, Tjeertes, Jorrit, Galanty, Yaron, Forment, Josep V., Clague, Michael J., Urbé, Sylvie, Jackson, Stephen P.

Journal:

Nature Cell Biology

Year:

2014

Language:

english

File:

PDF, 1.98 MB

english, 2014

12

MicroRNA hsa-miR-135b Regulates Mineralization in Osteogenic Differentiation of Human Unrestricted Somatic Stem Cells

Schaap-Oziemlak, Aneta M., Raymakers, Reinier A., Bergevoet, Saskia M., Gilissen, Christian, Jansen, Bastiaan J.H., Adema, Gosse J., Kögler, Gesine, le Sage, Carlos, Agami, Reuven, van der Reijden, Be

Journal:

Stem Cells and Development

Year:

2010

Language:

english

File:

PDF, 991 KB

english, 2010

13

Diverse Ways to Control p27Kip1 Function: miRNAs Come into Play

le Sage, Carlos, Nagel, Remco, Agami, Reuven

Journal:

Year:

2007

Language:

english

File:

PDF, 630 KB

english, 2007

14

Neddylation Promotes Ubiquitylation and Release of Ku from DNA-Damage Sites

Brown, Jessica S., Lukashchuk, Natalia, Sczaniecka-Clift, Matylda, Britton, Sébastien, le Sage, Carlos, Calsou, Patrick, Beli, Petra, Galanty, Yaron, Jackson, Stephen P.

Journal:

Year:

2015

Language:

english

File:

PDF, 3.35 MB

english, 2015

15

Immense Promises for Tiny Molecules: Uncovering miRNA Functions

Sage, Carlos le, Agami, Reuven

Journal:

Year:

2006

Language:

english

File:

PDF, 364 KB

english, 2006

16

Synthetic lethality between PAXX and XLF in mammalian development

Balmus, Gabriel, Barros, Ana C., Wijnhoven, Paul W.G., Lescale, Chloé, Hasse, Hélène Lenden, Boroviak, Katharina, le Sage, Carlos, Doe, Brendan, Speak, Anneliese O., Galli, Antonella, Jacobsen, Matt,

Journal:

Genes & Development

Year:

2016

Language:

english

File:

PDF, 717 KB

english, 2016

17

CRISPR: A Screener’s Guide

le Sage, Carlos, Lawo, Steffen, Cross, Benedict C. S.

Journal:

Year:

2019

Language:

english

File:

PDF, 1015 KB

english, 2019

18

A Flexible, Pooled CRISPR Library for Drug Development Screens

Blanck, Maximilian, Budnik-Zawilska, Milka B., Lenger, Steven R., McGonigle, John E., Martin, Glynn R.A., le Sage, Carlos, Lawo, Steffen, Pemberton, Helen N., Tiwana, Gaganpreet S., Sorrell, David A.,

Journal:

The CRISPR Journal

Year:

2020

File:

PDF, 1.26 MB

2020